Between ubiquitous overdose videos and an onslaught of headlines, heroin seems to be everywhere. But Warning: This Drug May Kill You, which premieres Thursday at the Tribeca Film Festival and on HBO May 1, is the one thing I would urge everyone to watch, especially if you’re in the minority of Americans who don’t already know someone scorched by the opioid epidemic that is killing nearly 100 people a day. The reason: Director Perri Peltz makes you get what these people—sisters, friends, colleagues—are up against. She helps you see the arm instead of the needle. One of the most gripping stories Peltz follows is that of Stephany Gay, a young woman who was prescribed Dilaudid, Vicodin, and Oxycontin for kidney stones when she was 16. After the pain wore off, she got hooked on the meds and shared them—as she shared everything—with her older sister, Ashley.

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