Regular exercise doesn’t erase the higher risk of serious illness or premature death that comes from sitting too much each day, a new review reveals. Combing through 47 prior studies, Canadian researchers found that prolonged daily sitting was linked to significantly higher odds of heart disease, diabetes, cancer and dying. And even if study participants exercised regularly, the accumulated evidence still showed worse health outcomes for those who sat for long periods, the researchers said. However, those who did little or no exercise faced even higher health risks. “We found the association relatively consistent across all diseases. A pretty strong case can be made that sedentary behavior and sitting is probably linked with these diseases,” said study author Aviroop Biswas, a Ph.D. candidate at Toronto Rehabilitation Institute-University Health Network.

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